Do antidepressants make you hungrier?
Mia Moss
Published Jan 21, 2026
An improved mood while taking an antidepressant, for example, may increase your appetite, leading to weight gain. Don't stop taking your drug right away even if you do gain a little bit of weight.
Why do antidepressants make you hungry?
Antidepressants interfere with serotonin, the neurotransmitter that regulates anxiety and mood while also controlling appetite. In particular, these changes may increase cravings for carbohydrate-rich foods, such as bread, pasta, and desserts. When people are depressed, their appetites are affected.Do antidepressants cause overeating?
While some people gain weight after starting an antidepressant, the antidepressant isn't always a direct cause. Many factors can contribute to weight gain during antidepressant therapy. For example: Overeating or inactivity as a result of depression can cause weight gain.How do you stop hunger on antidepressants?
Avoid eating protein at dinnertime if your medications make you snack all evening. By eating only a starchy carbohydrate, like pasta or a large baked potato along with vegetables for dinner, your brain will make enough serotonin to keep you satisfied and full until bedtime.Which antidepressants cause the most weight gain?
Tricyclic antidepressants such as amitriptyline and tetracyclic antidepressants such as mirtazapine are linked to the most weight gain.Why do you gain weight with antidepressants and mood stabilizers?
What is the best antidepressant for weight loss?
Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.How much weight can you gain on antidepressants?
Experts say that for up to 25% of people, most antidepressant medications -- including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Lexapro, Paxil, Prozac, and Zoloft -- can cause a weight gain of 10 pounds or more.Does Zoloft make you hungry all the time?
Since medications like sertraline are often prescribed for the long term, even a small increase in your appetite can eventually have a significant effect on your weight.Which causes more weight gain Prozac or Zoloft?
That being said, one study published in 2016 in the Journal of Clinical Medicine found that Zoloft can lead to an overall greater weight gain than Prozac when taken long-term. The study found that people taking Prozac for two years gained an average of 4.6 pounds.How can I control my appetite due to medication?
Here are some ways to lose weight gained due to medication use:
- Switch to a different medication. The first strategy to consider involves changing medications. ...
- Lower medication dosage. ...
- Limit portion sizes. ...
- Exercise. ...
- Eat more protein. ...
- Talk to a dietitian. ...
- Avoid alcohol. ...
- Get enough sleep.
Do antidepressants slow metabolism?
And yes, certain antidepressants and other medications may increase appetite. However, most medications do not alter metabolism, per se. Thus, weight loss can still occur when attention is given to other factors, including the composition and timing of dietary intake.Is sertraline making me fat?
Zoloft (sertraline) may lead to a small weight gain ranging from 1% to 1.6% of initial body weight when used over 6 months to 1 year. For example, in a 150 lb (68 kg) person, this would equal an added 1.5 to 2.4 lbs (0.7 to 1.1 kg) of weight.Do SSRI make you gain weight?
Research suggests that the amount of weight typically gained while on an SSRI is modest. 1 While from the outside, a few extra pounds may seem like a small sacrifice to make in exchange for positive changes to your mental health, weight gain can be a bothersome side effect.Do antidepressants change your personality?
Antidepressant medications taken by roughly 7% of American adults cause profound personality changes in many patients with depression, far beyond simply lifting the veil of sadness, a study has found.Which antidepressants do not cause weight gain?
Antidepressants that do not cause weight gain
- Effexor (venlafaxine)
- Wellbutrin (bupropion)
- Nefazodone (however, this is rarely used because it can cause severe liver problems)